New Hope For Regrowing Severed Limbs, Just Like Lizards' TailsSome lizards and amphibians have the ability to regrow severed tails or limbs--in fact the blue-tailed skink abandons its tail intentionally to distract predators. But humans despite our amazing advancements in the field of spying on each other are typically thought to lack this superpower-like ability. But in fact we're more like blue-tailed skinks than you'd think!Back in 2010 a woman named Deepa Kulkarni lost the tip of her finger to an altercation with a slammed door. She was able to grow it back with the use of a powder made of ground-up pig bladder (seriously) called MatriStem which according to ACell the company that makes it incorporates into the surrounding tissue during the healing process and leaves new tissue where scar tissue formation is normally expected. Basically MatriStem works as a sort of scaffolding--it attracts stem cells from they think the bone marrow which comes out and builds tissue on top of the MatriStem powder rather than merely scarring over. It worked for Kulkarni but it was theorized that it only worked because she retained a bit of the nail on her partially-severed finger.Dr. Mayumi Ito a stem cell biologist and dermatologist at NYU's Langone Medical Center recently published a paper in which he and his team examined exactly how this works and confirmed the theory about the fingernail. Turns out the human fingernail includes a group of stem cells that promote cell growth--not just the rest of a fingernail but tissue and even bone. Ito named this family of stem cells Wnts pronounced wints and found that in mice these cells produce chemicals that regrew bone and flesh.So what if in the absence of natural Wnts you used genetic engineering to force tissue to produce these proteins? Would the natural effect--regrown tissue and bone--follow? Amazingly yes. When they forced the production of Wnts in mice the team managed to regrow bone and tissue without any of the natural stem cells being present at all. This has huge implications for the treatment of amputations--the experiment was only performed on mice but if the technique holds true for humans this could be the beginning of the end for lost limbs. [via MedicalDaily]This is very exciting for regenerative medicine. How far can this go? Will we one day be able to deliberately cause damage to have more complex body parts regenerate in a controlled way (eg. the removal of a damaged/diseased portion of lung)? If we can continue to learn about this natural ability we may be able to regenerate much more than just extremities.Having lost my right leg above the knee when I was 14 due to a 130mph motorcycle wreck by father caused and being nearly 40 now.... I wonder what potential this has for regrowing my leg.I wonder if there might be side effects like an increased potential for cancer...I wonder how long it would take to regrow such a large appendage.... I wonder if it would be covered by insurances.... specifically Medicare and or state Medicaid...And I wonder if I've got enough time left in my life to have it done.... I volunteer to undergo the procedure.Pretty good for almost any aliment except spammers. So a tube of this stuff in a chalk gun is all we need to fix any number of issues assuming the host has good tissue to start? This is a good advance indeed.1 - Ground up pigs bladder 1 - extract of human finger nailAll you need to do is say the magic words and your limb regeneration potion is done. That concludes todays potions lesson.Amazing. Don't see why it would not also work on spinal cord injuries? Also need to see what happens when it interacts with cancer. I do wonder if there are a relative unlimited amount of the stem cells in your bone marrow or if there are limits that if exceeded could bring other health issues.Start working at home with Google! It's by-far the best job Ive had. Last Monday I got a new Alfa Romeo from bringing in $7778. I started this 9 months ago and practically straight away started making more than $83 per hour. I work through this link www.Bling6.comcan someone tell me how to contact the folks involved in this research? I have the very same injury as Deepa Kulkarni having retained a portion of the nail on my left index finger ..I knew it was possible.When my child was born with a severe heart anomoly sentencing her to global developmental retardation Mental and physical I embarked on learning everything available on the specific condition and anomolies in general. I read from a peer reviewed research paper that in the early 1960's Johns Hopkins had verified a case of finger regeneration at that facility. Further investigation showed the occurrence was not a one-of miracle. In each instance however individual cases were considered god caused miracles and as such closeted against widespread dissemination lest being branded a heretic as was the first surgeon who recommended hand washing prior to surgeries.. Enough scientific data was collected to state conditions for expected successful regeneration. The oldest patient was 11 years old.The amputation had to be no higher than the 2nd wrinkle at the 1st finger joint; AND the site had to be free of any intervention save bandage; no anasthesia no cauterizing no suturing. It was stated that the finger would regenerate bone nail bed nerves tissue scar tissue free. However any interventions beyond bandage were cited as non reversible hurdles.In a different vein I have used accupressure with 2 persons with brilliantly reconstucted hands that were years laterstill non functional except for waving where feeling mobility and normal strength returned in relatively quick order by applying deep semi blunt mechanical probe to the same sided foot in the area hand damage had occurred.Hitting the precise point(s)always brings forth an expletive confirmation from the subject. I can only suspect that either shock or perhaps more likely the well intended anaesthesia had caused the brain to lose track of the damaged body part that needed it's healing concentration. So much learned so much valuable knowledge forgotten; SO MUCH to learn and relearn. TCM meridian theory would seem to explain why squeezing you right big toe sends a nerve message to your right thumb. My child by the way with the help of imported ages old German natural medicines went on to be cited as the first child with that particular cardiac anomoly to develop normally she was brilliant as a person an intellect an intelligence and physically within her PUFF limitations. Gymnastics skiing skating a few of her sports.To much later being lost in an operating procedure deemed relatively (87%) safenot imminently life threatening anyway except for her. An unforseen. But strange that we consider it a truth that we religiously at least nominated and self elected as the superior being by god appointed decree do not to a person believe unequivocally in the body's ability to self heal. And yet from Johns Hopkins early archives are cases of child organ anomolies healing when the environmental issues of nutrition etc were brought to a healthy perfect prenatal optimal level. Why would avaians amphibians and on to ad nozium be given that ability; why do raccoons foxes know how to cast a broken leg; to find the perfect site for recovery water food shelter prey vulnerability reduced. When bloodletting Europeans stumbled on Turtle Island North America shores the Landowner North American Amerindians had a complete Pharmacopea inferiorly chemically immitated and patented today were doing surgery including neuro surgery used anaesthetics including sub cu and injection; and employed periodic and permanent herbal pregnancy contraception. Our Euopean ancestors made crosses part of door and window constuction; constructed front and back doors to confuse the demons who could only enter by the front door; blood let; applied leeches(their most scientifically based bit of medicine); administered arsenic.Declared every last grain of any resource theirs to consume until depletion. ( Sounds like us.??) And we still depend on hanging garlic to defend against the unseeable evil spirits. Only now it is encapsulated iv'd........and sold to us by the gods. All the while plugging our gullets with newest petro chem created FRANKENFOODS SUCH AS GLUCOSE FRUCTOSE HIGH FRUCTOSE CORN SYRUP nitites sugar now even in table salt genetically modified wheat all canola/thus usafe canola oil; corn.... While proven heath promoting andhealing methods are poopooed it's geniuses burned at the stakeby Quackbusters; it's proponents ridiculed. Like our 1st Natiions and African ancestors were called savage heathens. My elderly office manager says we are the lesser monkeys.When my child was born with a severe heart anomaly sentencing her to global developmental retardation Mental and physical I embarked on learning everything available on the specific condition and anomalies in general. I read from a peer reviewed research paper that in the early 1960's Johns Hopkins had verified a case of finger regeneration at that facility. Further investigation showed the occurrence was not a one-of miracle. In each instance however individual cases were considered god caused miracles and as such closeted against widespread dissemination lest being branded a heretic as was the first surgeon who recommended hand washing prior to surgeries.. Enough scientific data was collected to state conditions for expected successful regeneration. The oldest patient was 11 years old.The amputation had to be no higher than the 2nd wrinkle at the 1st finger joint; AND the site had to be free of any intervention save bandage; no anasthesia no cauterizing no suturing. It was stated that the finger would regenerate bone nail bed nerves tissue scar tissue free. However any interventions beyond bandage were cited as non reversible hurdles.In a different vein I have used accupressure with 2 persons with brilliantly reconstucted hands that were years laterstill non functional except for waving where feeling mobility and normal strength returned in relatively quick order by applying deep semi blunt mechanical probe to the same sided foot in the area hand damage had occurred.Hitting the precise point(s)always brings forth an expletive confirmation from the subject. I can only suspect that either shock or perhaps more likely the well intended anaesthesia had caused the brain to lose track of the damaged body part that needed it's healing concentration. So much learned so much valuable knowledge forgotten; SO MUCH to learn and relearn. TCM meridian theory would seem to explain why squeezing you right big toe sends a nerve message to your right thumb. My child by the way with the help of imported ages old German natural medicines went on to be cited as the first child with that particular cardiac anomoly to develop normally she was brilliant as a person an intellect an intelligence and physically within her PUFF limitations. Gymnastics skiing skating a few of her sports.To much later being lost in an operating procedure deemed relatively (87%) safenot imminently life threatening anyway except for her. An unforseen. But strange that we consider it a truth that we religiously at least nominated and self elected as the superior being by god appointed decree do not to a person believe unequivocally in the body's ability to self heal. And yet from Johns Hopkins early archives are cases of child organ anomolies healing when the environmental issues of nutrition etc were brought to a healthy perfect prenatal optimal level. Why would avaians amphibians and on to ad nozium be given that ability; why do raccoons foxes know how to cast a broken leg; to find the perfect site for recovery water food shelter prey vulnerability reduced. When bloodletting Europeans stumbled on Turtle Island North America shores the Landowner North American Amerindians had a complete Pharmacopea inferiorly chemically immitated and patented today were doing surgery including neuro surgery used anaesthetics including sub cu and injection; and employed periodic and permanent herbal pregnancy contraception. Our Euopean ancestors made crosses part of door and window constuction; constructed front and back doors to confuse the demons who could only enter by the front door; blood let; applied leeches(their most scientifically based bit of medicine); administered arsenic.Declared every last grain of any resource theirs to consume until depletion. ( Sounds like us.??) And we still depend on hanging garlic to defend against the unseeable evil spirits. Only now it is encapsulated iv'd........and sold to us by the gods. All the while plugging our gullets with newest petro chem created FRANKENFOODS SUCH AS GLUCOSE FRUCTOSE HIGH FRUCTOSE CORN SYRUP. While proven heath promoting andhealing methods are poopooed it's geniuses burned at the stakeby Quackbusters; it's proponents ridiculed. Like our 1st Natiions and African ancestors were called savage heathens. My elderly office manager says we are the lesser monkeys.